Introduction Peer support has been effective in improving self-management behaviors and health outcomes among individuals with diabetes. Under-resourced, rural organizations may struggle to employ individuals delivering peer support due to limited resources. Peer support programs involving volunteers may serve as an effective, low-cost solution to the need for diabetes education and support; however, factors affecting their retention remain understudied. Solutions are needed given health disparities in diabetes among Latinos in the US and disproportionately high rates in their countries of origin. Purpose This study examined factors which may affect volunteer retention including volunteer motivations, perceived organizational support, perceived efficacy of organizational training, and self-efficacy. Additionally, this study explored volunteer peer leaders’ satisfaction with the Puentes program to identify factors which may strengthen interest to continue volunteering. Methods Data were collected from 34 predominantly Mexican-origin volunteer peer leaders who assisted patients at clinics located on the US/Mexico border with their diabetes management. Peer leaders completed surveys with open- and close-ended questions at three time points: baseline, 6-months and 12-months. Quantitative and qualitative data analyses were guided by the Volunteer Process Model. Results Using quantitative data, self-efficacy as a peer leader at 6 months was associated with interest to continue volunteering at 6-months. In addition, satisfaction with support from the Puentes program at 12-months was associated with interest to continue volunteering at 12 months. The qualitative data indicated that the relationship between volunteer peer leaders and their patients was most important for the volunteer experience. Conclusion Future research should focus on increasing Latino volunteer peer leaders’ self-efficacy and satisfaction and examine how organizations can support the development of the patient and peer leader relationship. Practitioners should consider appealing to volunteer peer leaders’ altruistic motivations to promote retention.