The problems inherent to High energy photon imaging require alternate modes of collimation. Whereas the gamma camera's physical collimator typically reduces the intensity of the photons by more than 99.9%. The Compton camera achieves higher sensitivity by using the photons which are no longer required to pass through a physical collimator. The sensitivity of the Compton Camera has been shown to be 2 to 3 orders of magnitude larger than the sensitivity of a physically collimated gamma Camera. The electronic collimation is inherently 3D and is inherently suited for tomography. Software was developed as part of this thesis to process MCNPX-PTRAC output to simulate a triple Compton scatter camera in the range of 140 keV to 511 keV. The results of the simulations demonstrated the effects of varying detector's design parameters such as energy and spatial resolution. The inaccuracies in the Monte Carlo MCNPX software in particular with respect to the Doppler broadening subroutines were noted and discussed.
