Background Based on the Behavioral Ecological Model, this study explored the social history and contextual variables within gentlemen's clubs as predictors of prostitution behavior in exotic dancers. Methods Data were gathered from face-to-face surveys with exotic dancers in San Diego County (N=123). Results A multivariate logistic regression showed that childhood neglect, marijuana use, and allowance of customer touching were significant predictors of prostitution behavior. Discussion in context of previous studies regarding employment at gentlemen's clubs, women involved in exotic dancing may be at risk of engaging in prostitution behavior. Results warrant more complete quantitative studies on the involvement in prostitution by exotic dancers. Results also support early intervention studies that might prevent or reduce prostitution practices and possible sexually transmitted infections and HIV.