Numerous fields of study and professions employ the 'neighborhood' as the most basic unit to represent a distinct social or geographical area. In reality, neighborhoods are not that simple and there is no accepted set of rules for establishing neighborhood boundaries and definitions. Neighborhoods change in many ways over time, sometimes for the good of the residents, other times to the detriment, but changes always have an effect on the residents, including in the area of health outcomes. One of the primary goals of the Health, Poverty and Place in Accra, Ghana project is to establish methods of delineating neighborhoods in developing cities where, due to lack of mobility, neighborhoods play an increasingly important role in shaping health outcomes of the residents. This thesis takes an exploratory approach in evaluating three neighborhoods in San Diego, California and uses various methods including surveys, demographic data, visual representations and interviews in an attempt to model neighborhood boundaries and definitions with the hope that the model can then be applied to neighborhoods in developing cities. Various theories are taken into consideration, including the theory of neighborhood collective efficacy, broken windows, weak ties and social capital.