Intraskeletal oxygen stable-isotope ratios (δ18O) and minor element ratios (Mg/Ca) were examined in modern Mytilus californianus specimens to test the hypothesis that these variables record ambient seawater temperature, and therefore can be measured in fossil specimens as a means of reconstructing paleotemperature. Specimens representing a range of ontogenetic stages and two extreme intertidal positions were collected monthly for one year from Santa Cruz, CA. While general linear modeling (GLM) of various monitored environmental parameters revealed temperature as the primary explanatory variable, the best goodness-of-fit GLMs for δ18O and Mg/Ca explained only 37.1% and 28.5% of variation, respectively, with additional significant variance attributable to intertidal positions and specimen size. Thus, M. californianus appears to be an unreliable means to reconstruct paleotemperature given the large amount of unexplained variation in intraskeletal δ18O and Mg/Ca and the role of variables effectively unknowable in the fossil record (e.g., intertidal position).