This case study examines academic performance of student-athletes who are considered academically at-risk when they enroll at San Diego State University. To conduct this study, a mixed method research design was employed using Astin's Inputs-Environment-Outcomes (I-E-O) model as the theoretical framework. National Collegiate Athletic Association's GOALS survey data and academic performance levels of the 2012-13 at-risk student-athlete population were analyzed to report significant findings. In addition, qualitative data were collected from institutional leaders that have a vested interest in the academic performance of student-athletes. The results of the study indicated that the at-risk population's mean cumulative GPA was less than all other student-athletes at 2.69 and 2.84, respectively. There were also statistically significant differences in mean GPA among the at-risk population with regard to gender, major, sport participation, and year in school. However, incoming eligibility index score did not have a statistically significant impact on GPA. Correlation between high school GPA, index score, and college GPA indicated a significant relationship between high school GPA and college GPA. Analysis of the survey data revealed 21 of the 90 variables as statistically significant correlations with GPA, 10 of which also correlated positively or negatively among the predictor variables. Moreover, regression modeling, including all predictor variables, accounted for 53% of the variance in cumulative GPA and resulted in seven significant predictors of mean GPA. By and large, campus leaders reported that at-risk student-athletes are supported in their quest to graduation. This research may provide insight for institutions and athletic departments to improve at-risk student-athlete academic development.