Binge drinking is commonly practiced by young adults especially on college campuses. It is accompanied by a range of health, cognitive, and social problems. Given the importance of social-emotional and cognitive-academic domains for everyday functioning, the present study investigated behavioral and brain indices of affective and memory processes as a function of binge drinking patterns. Sixty eight participants (23.3 ± 3.3 yrs) were assigned to two groups based on their drinking habits: binge drinking (BD) participants reported drinking heavily with at least 5 binge episodes in the last 6 months, whereas light drinkers (LD) reported no more than one binge episode in the last 6 months (n = 34 each). In the first of two sessions participants provided subjective ratings of negative, positive, erotic, and neutral pictures selected from the International Affective Picture System. A recognition test followed after a 48-hr interval making it possible to examine encoding indices that were predictive of later recognition, and episodic memory retrieval. Electroencephalography (EEG) signal was recorded with a 64-channel system and analyzed in time-frequency domain with Morlet wavelets in theta band (4–7 Hz) and in time-domain as event-related potentials (ERPs). A series of mixed-design ANOVAs were conducted on the behavioral and brainbased measures across both tasks. Subjective ratings and recognition accuracy were equivalent across both groups. However, EEG measures revealed that: (1) during emotional rating, BD group showed attenuated theta power to negative and positive (vs. neutral) pictures and reduced late positive ERP responses to erotic (vs. neutral) pictures relative to LDs; (2) during encoding, the late positive potentials associated with subsequent memory effects were reduced in BDs; (3) during retrieval, BDs had weaker theta power to the recognized old pictures. These results suggest that binge drinking is associated with altered neurophysiological indices of affective and memory functions that are reflected in blunted cortico-limbic integrations via theta oscillations and late ERPs. In the context of absent performance differences, such EEG deficits could be sensitive biomarkers of the subtle brain dysfunctions that accompany binge drinking. These neural disturbances may provide implications for the diagnosis and preventions of the development of alcohol disorders.